Rolf Apweiler is a director of European Bioinformatics Institute (EBI) part of the European Molecular Biology Laboratory (EMBL)[7][8] with Ewan Birney.

[9][10] Apweiler gained his PhD in biochemistry from Heidelberg University.

He has been joint head of the Protein and Nucleotide Data (PANDA) Group since 2007.

The PANDA group is involved in several international collaborations like the Human Proteome Organization (HUPO) Proteomics Standards Initiative.

Apweiler is a member of the Nomenclature Committee of IUBMB, the FlyBase advisory board, the committee of the Helmholtz Centre for Infection Research (HZI) and the advisory board of the Human Proteome Resource (HPR).