Roma Trastevere railway station is situated at Piazza Flavio Biondo, southwest of the city centre.

The original Roma Trastevere railway station was more centrally located, at Piazza Ippolito Nievo.

In recent years, the present station has been the subject of renovations and improvements commissioned by Centostazioni.

Operationally, it was previously classified as a junction station, but in 1990 it was downgraded to the status of a stopping point.

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