Romain De Loof (born 6 March 1941) is a retired Belgian cyclist.

After winning the UCI Motor-paced World Championships in 1962 and 1963 in the amateurs category, he turned professional and won another three medals in 1965–1967, including one gold.

[2] Between 1965 and 1970 he competed in 56 six-day track races, winning in Milan (1965; with Rik Van Steenbergen), Amsterdam and Rotterdam (both 1969; both with Peter Post).

After a crash in the race of Gent-Wevelgem in 1970, he suffered a triple fracture of the pelvis and had to pause for a year.

[3] He finally retired in 1975 and later acted as the manager of professional cycling teams Ebo-Cinzia en Marc-Zeepcentrale.