The Roman Catholic Diocese of Enugu (Latin: Enuguen(sis)) is a diocese located in the city of Enugu in the ecclesiastical province of Onitsha in Nigeria.

On November 12, 1962, the Diocese of Enugu was erected from ecclesiastical territory gained from the Metropolitan Archdiocese of Onitsha.

[1] On July 8, 2005, Enugu lost territory to the new Diocese of Awgu.

[2] The Cathedral is Holy Ghost Cathedral in Enugu.