It also has a co-cathedral, San Miguel Arcángel, in the city of Totonicapán.

[1] It was vacant until named Mario Alberto Molina Palma on July 14, 2011; having been headed until Monday, October 4, 2010, by Archbishop Oscar Julio Vian Morales, who was then named by Pope Benedict XVI to succeed Cardinal Quezada as Metropolitan Archbishop of Guatemala.

[2] It was erected on 27 July 1921 as the Diocese of Quetzaltenango, Los Altos, on territory split off from the Metropolitan Roman Catholic Archdiocese of Guatemala.

It was elevated and renamed to Archdiocese of Los Altos Quetzaltenango-Totonicapán on 13 February 1996.

It lost more territory on 31 December 1996 to establish the Diocese of Suchitepéquez-Retalhuleu, another suffragan.