The Diocese of Salto is a Latin Church ecclesiastical territory or diocese of the Catholic Church in Uruguay.

The Diocese of Salto covers four departments: Artigas, Salto, Paysandú, and Río Negro.

The Diocese of Salto is a suffragan diocese of the ecclesiastical province of the metropolitan Archdiocese of Montevideo.

The current bishop is Arturo Eduardo Fajardo Bustamante, who was appointed on 15 June 2020, transferring him from the Diocese of San José de Mayo.

This article on a Roman Catholic diocese in Uruguay is a stub.