Roman Plague of 590

[1] The epidemic began in early 590; Gregory's narrative is not specific but death came rapidly to infected patients and the chronicler describes the disease as a 'plague of the groin' (Latin: lues inguinaria), factors which aid its identification as bubonic plague.

[1] Gregory had previously served as an apocrisiarius, a kind of papal ambassador to the East Roman Empire, where he had likely been influenced by Byzantine practices.

[4] The seven processional groups were: 1) clergy, 2) abbots and monks, 3) abbesses and nuns, 4) men 5) married women 6) widows and 7) children (also perhaps including the poor of Rome).

[1] According to later legend, Pope Gregory saw a vision as the procession approached the mausoleum of the Roman emperor Hadrian, on the right bank of the Tiber near the Vatican Hill.

[5] In the 18th century, a bronze sculpture was set on the summit of Castel Sant'Angelo to commemorate the legend, portraying the winged archangel in Roman armour and designed by Peter Anton von Verschaffelt in 1753.

The vision of Pope Gregory at Castel Sant'Angelo , signifying the end of the plague, became a popular theme of medieval art. [ 1 ]
Statue of St Michael on Hadrian's Mausoleum, by Peter Anton von Verschaffelt (1753)