A longstanding member of the current iteration South Atlantic League since its inception, the Class A Atlanta Braves affiliate's history dates back to 1968 with the founding of the Greenwood Braves, sporting a roster featuring future major league talents such as Brett Butler, Steve Bedrosian, and Brian Snitker.

Sumter was a starting point for several major league talents, including an early stop for future Baseball Hall of Fame pitcher Tom Glavine.

In Sumter, the team also earned their first opportunity in the SAL Playoffs as the First Half Champion of the 1985 North Division, going on to lose to the Greensboro Hornets in 2 games.

The Macon Braves would serve as the last time the city would host a major-league affiliated minor league team.

Following the approval of a SPLOST tax, the city of Rome, Georgia, managed to entice the Braves organization, and as a result they became the new home of the Single-A affiliate starting with the 2003 season.

The SPLOST tax helped with entirely building their home, AdventHealth Stadium, and a high level of optimism followed the team to Rome.

The second half featured a much better effort, with help from two future Braves fan-favorites in Brian McCann and Jeff Francoeur, and Rome got to a 42–38 record to win the Southern Division in the second half of the season and advance to the Playoffs for the time ever in Rome, and the sixth time overall since the original inception of the team in Anderson in 1980.

Ingle served in the Braves organization for his entire 14 seasons prior to joining Rome, including two stops in 1993 and 2001 with Macon.

2007–2010 saw the Rome Braves unable to climb out of the lower part of the South Division, finishing with losing records in all 4 seasons.

Sporting one of the youngest clubs in full-season baseball, 2016 looked to be starting the same way under Ingle, with a 27–42 having them at 6th in the division heading into the midseason break.

Thanks to a pitching room featuring Mike Soroka, Kolby Allard, Max Fried, A. J. Minter, and Touki Toussaint, and two big time bats in the form of Ronald Acuña Jr. and Austin Riley, players that majorly make up most of the current major league roster for Atlanta gave Rome one of its biggest pushes and went on to finish the 2nd half with a 43–27 record, once again returning to the playoffs.

The announcement also included Rome's new league location, the newly created High-A East, with the Rome Braves joining former South Atlantic League opponents Asheville Tourists, Greensboro Grasshoppers, Greenville Drive, Hickory Crawdads, and Jersey Shore (formerly Lakewood) BlueClaws; alongside new opponents Aberdeen IronBirds, Brooklyn Cyclones, Hudson Valley Renegades, Wilmington Blue Rocks, Bowling Green Hot Rods, and Winston-Salem Dash.

[1] In 2022, the High-A East became known as the South Atlantic League, the name historically used by the regional circuit prior to the 2021 reorganization.