[4][citation needed] In 2012, Romeo Tan was the first among his fellow Star Search finalists to be given a supporting role in the critically acclaimed police procedural series C.L.I.F..

[citation needed] In 2013, Romeo Tan replaced Dai Xiang Yu, who was originally selected to play the role of Hong Khee Leong, as the male lead in the drama series Sudden.

[citation needed] In 2017, he participated in the films Dream Coder, When Duty Calls, and Life Less Ordinary that led to his second nomination for Best Actor and Best Theme Song in Star Awards 2018.

In May 2020, Tan revealed on his social media account that he had purchased an apartment unit at Marina One Residences⁠, a condominium development which is located at the Central Business District (CBD) in Singapore.

Prior to that, Tan had lived in a four-room HDB flat in Simei with seven of his family members; including his parents, his two brothers, his sister-in-law, his nephew and niece.

Hence, Tan often stayed over at the semi-detached house of his actor friend Elvin Ng, as it was nearer to Mediacorp's former and current studios at Caldecott Hill and one-north, and to have a quiet environment to memorise his lines.