Ronald Vance Mathis (born September 25, 1958) is a former professional baseball player.

He was a right-handed pitcher over parts of two seasons (1985, 1987) with the Houston Astros.

For his career, he compiled a 3-6 record, with a 5.93 earned run average, and 42 strikeouts in 82 innings pitched.

An alumnus of the University of Missouri, Mathis was born in Kansas City, Missouri.

This biographical article relating to an American baseball pitcher born in the 1950s is a stub.