"[8] In August 2017, Justin Trudeau's Liberal government appointed Ambrose to a 13-member NAFTA advisory council that would provide opinion and feedback on the negotiations with the United States and Mexico.

On February 16, 2005, she made headlines after making a remark in Parliament directed at Liberal Social Development Minister Ken Dryden about the Liberal national child care plan: "Working women want to make their own choices; we don't need old white guys telling us what to do.

[26] On April 7, 2006, Ambrose announced that Canada could not meet its targets under the Kyoto Protocol and must set more realistic goals for cutting greenhouse gases.

[27] On April 13, 2006, Ambrose stopped an Environment Canada scientist, Mark Tushingham, from speaking at the launch of his science fiction novel Hotter than Hell, set in a dystopian future caused by global warming.

Still, Ambrose's spokesperson said the speech was billed as coming from an Environment Canada scientist speaking in an official capacity and thus out of the process.

[28][29] On April 25, 2006, Ambrose expressed her support of the (now defunct) Asia-Pacific Partnership on Clean Development and Climate as an alternative to the Kyoto Protocol, because it includes China and India.

"[31][32] In June 2006, opposition discontent over Ambrose's actions as environment minister prompted the NDP and the Bloc Québécois to try to table a motion in the Commons environmental committee calling for her resignation.

"[34] On October 19, 2006, Ambrose introduced a Clean Air Act [citation needed] that aimed to reduce greenhouse emissions starting in 2020, cutting them to about half of the 2003 levels by 2050.

She also introduced other regulations to industries and vehicles and possible cooperation between the federal government and the provinces to create a system that would report air emissions.

[38] On January 19, 2010, Ambrose succeeded Christian Paradis and was appointed as the new Minister of Public Works and Government Services, where she introduced a major project to improve the way the government administers its pay and pension systems and "which will modernize service, introduce efficiencies, and improve our stewardship responsibilities in those areas.

The International Day of the Girl Child was formally proposed by Canada in the United Nations General Assembly as a resolution.

On December 19, 2011, the United Nations General Assembly voted to pass a resolution adopting October 11, 2012, as the inaugural International Day of the Girl Child.

Viewing the motion as an attempt to re-open the debate on abortion laws, Canadian pro-choice groups and Commons opposition parties considered her vote inconsistent with her ministerial role[42][43] and prompted a call for her resignation.

[47] On June 11, 2015, she made headlines for being "outraged" that (in a unanimous decision) the Supreme Court of Canada expanded the definition of what constituted medical marijuana to include oils, teas, brownies, etc., from its previous limitation to dried leaves, arguing "Marijuana has never gone through the regulatory approval process at Health Canada, which requires rigorous safety reviews and clinical trials with scientific evidence.

If passed, this bill would require judges in Canada to undergo training on sexual assault law, involving education on rape myths, stereotypes about victims, and the impact of trauma on memory.

[56] The JUST Act gained widespread support from experts and victim advocacy groups and was subsequently passed unanimously by the House of Commons.

[57] In May 2017, Ambrose announced to her caucus that she would leave federal politics at the end of the spring session of Parliament, in June 2017, several weeks after her successor as Conservative leader was chosen.

[61] She joined the Canada Institute at the Woodrow Wilson International Center for Scholars, a Washington, D.C.–based think tank, as a visiting fellow focused on Canadian–American trade and to lead the organization's campaign to educate officials in both countries about the benefits of an integrated North American economy.

She Leads is a non-profit organization based in Alberta that encourages women to run for office and participate in public life.