In December 1908, the family moved into the building which still stands: Franklin, Eleanor, and their children, James and Anna, into No.

Eleanor, one of the leading Democrats at the time, was largely involved in Franklin Roosevelt's decision making and other activities.

It was also at Roosevelt House where he offered positions to individuals, including Frances Perkins, the "first female to serve as a Cabinet Secretary.

"[2] Before his inauguration in March 1933, Franklin Roosevelt held meetings there to discuss what was to be done within the First Hundred Days.

[2] On November 9, 1932, the day after the presidential election, Franklin Roosevelt made his "first radio address to the American people as president-elect".

[2] In 1941, when Sara Delano passed away, Franklin put the property up for sale, but a nonprofit group offered to buy it for Hunter College.

The Roosevelt House was being repaired while preserving "the historically significant floor-plan of the first through fourth floors".