After graduating from Thammasat University, Rosana formed the NGO "Traditional Medicine for Self-Curing", later renamed the "Thai Holistic Health Foundation".

She studied medicinal plants in the district and helped form the "Natural Medication and Herb Interest Group" there.

[3] Rosana worked for many years as a women's rights activist[4] for the Thai Health Foundation, calling for the resignation of Rakkiat Sukthana on corruption charges.

She also called for the resignation of Purachai Piumsomboon over a supposed cover-up of the spread of bird flu in Thailand.

[5][failed verification][6] She represented a coalition of over 30 NGOs in an appeal against a government plan to establish special economic zones around Thailand.