Rosanna Jeanne Reardon was born on June 8, 1985[2][3] in Seattle, Washington, where she was raised alongside her younger sister Molly Lu.

[6][7] She originally wanted to become an actress[8] and, after attending Pacific Lutheran University, she moved to Los Angeles to pursue acting.

[15][16] She has since received several accolades; in 2013, she won the Shorty Award for Best Foodie, Chef, or Food Lover in Social Media.

[17][18][19][20][21][22] In 2018, Pansino officially reached 10 million subscribers on YouTube, so she was given a Diamond Play Button by the company.

[23] According to CNBC and Forbes,[24] Pansino has remained one of the highest-paid YouTubers, reporting her to have made seven figures each year through sponsorships and advertisements.

"[15] Pansino has collaborated with several other YouTubers, including iJustine,[26][27] the Merrell Twins,[28] Rebecca Zamolo,[29] and MatPat.

[35] She stated in an interview with Forbes that "I don't want to miss an upload; I'm just not going to do that to my community, they've shown up for me and been so supportive of me, and in exchange I've been there for them—there's always going to be a video waiting for them on Saturday.

"[35] In 2021, she said in a Forbes interview "that around 60 hours of work go into a typical cooking video," due to the amount of time needed to experiment, assemble, bake, and film.

[35] As an actress, Pansino appeared on Season 2 of VH1's Scream Queens, a reality series in which the prize was a role in one of the Saw films; she ended in 9th place.

[36] Following this, Pansino appeared in small roles on shows such as Parks and Recreation and CSI: Crime Scene Investigation.

[53] Pansino began her business ventures in August 2017,[54] releasing a baking line in collaboration with cooking company Wilton.

[55] The set ranges from cooking tools and products intended more for the use of beginners, with the items including measurements and guides on each.

[56] She began hosting in 2019, making an appearance as a guest judge on Netflix original competitive-baking show Nailed It!.

[65] On December 17, 2019, Pansino announced throughout her social media outlets that her father, who appeared in several of her videos, had died as a result of leukemia, which he had been fighting for six years.