Rose Melville (January 30, 1867[a] – October 8, 1946) born Rosa Smock,[3] was an American stage actress famous for playing one character her whole career, "Sis Hopkins".

[4] Rosa Smock was born in Terre Haute, Indiana, the youngest of four daughter of Rev.

In 1894 a play called Zeb was produced in which Melville performed the Sis Hopkins character for the first time.

The Sis Hopkins character appeared in three more plays Little Christopher, The Prodigal Father;1896–97 and By the Sad Sea Waves; 1898–99.

In 1918 Goldwyn Pictures produced a feature film version of the Sis Hopkins play starring Mabel Normand.