As an actress she appeared in well over 30 films and television series, including Up Close & Personal (1996) and Rendition (2007), as well as, among others, Generations, Dynasty, CSI: Miami, JAG, ER and Babylon 5.

[10] In 1972 after winning a national piano competition in Iran, she was invited by Queen Farah Pahlavi to play at a Command Performance.

A graduate of San Francisco State University with two degrees in Music, she won an invitation to study drama at the American Academy of Dramatic Arts[11] and the historic Pasadena Playhouse.

She has since appeared in numerous notable television shows, films and plays, acting in a wide range of roles opposite many of Hollywood's leading actors.

She has had recurring roles on Days of Our Lives, Chicago Hope, Beverly Hills, 90210, The Young and the Restless and in 2008 she joined the cast of ABC's General Hospital as Farah Mir.

She played the role of Nuru Il-Ebrahimi, opposite Reese Witherspoon in New Line Cinema's Rendition, directed by Oscar-winning director Gavin Hood.

Her 30-minute testimony and plea to the U.S. government, ultimately prompted Congressman Chris Smith (R-NJ) to travel to war-torn Iraq to witness matters for himself.

She addressed the crowd of demonstrators and the media voicing her opposition at the removal of article 50 and its consequences for the minorities in Iraq in particular the Assyrians.

[44] On 24 February 2007, Malek-Yonan was a keynote speaker at an open forum in Anaheim, California, discussing the persecution of the Copts and the plight of Christians in the Middle East.

[48] On December 20, 2010, Malek-Yonan, was invited by the Simon Wiesenthal Center Museum of Tolerance to speak at a press conference to address the escalating crisis and the deadly attacks on the Assyrians in Iraq.

[53] For her numerous contributions as an actress, artist, director, author and activist, in March 2008, Malek-Yonan was awarded for Excellence in Arts and Entertainment by the Iranian American Political Action Committee (IAPAC).

The Crimson Field is an historical and literary epic novel, set in Urmia, Iran, Russia and San Francisco, California.

[91] It was features in the Winter 2007's fourth issue of MAKE, a Chicago Literary Magazine[92] and chosen as required reading by Professor Ellene Phufas for a World Literature class for the SUNY system (State University of New York) to represent a work about the Christian Genocides in Asia Minor.