Ross Alley lies between and is parallel to Stockton and Grant, running one city block between Jackson and Washington.

[11] According to a 1901 article, "Ross [A]lley is thought to be the spot in San Francisco where the souls of the dead can most easily come and where the evil spirits are forbidden to exercise their powers".

[12] The main entrance to the Golden Gate Fortune Cookie Company, a popular tourist destination, is located in Ross Alley.

The building used to house a sewing factory, owned by Henry Pon Lee, who vacated the premises during the late 1960s.

In the early 20th century, the Siberia Club, at 25-27-29 Ross Alley, run by Yee Mee, "king of the Chinatown gamblers" and head of the Hop Sing Tong,[13] was one of the more notable gaming establishments.