He is the founding director of the non-profit Lives in the Balance, and developed and executive produced the documentary film, The Kids We Lose.
Greene's research has been extensively published in academic journals and he and the CPS model have been mentioned in popular media.
He advocates against punitive, exclusionary disciplinary practices, including detention, suspension, expulsion, corporal punishment, restraint, and seclusion.
Greene's books The Explosive Child and Lost at School focus on children and adolescents who are compromised in the realms of flexibility, frustration tolerance, emotion regulation, and problem solving, resulting in frequent and sometimes severe temper outbursts and noncompliance.
In his books, Greene outlines a treatment model called "Collaborative & Proactive Solutions" for helping such youth in families, schools, and therapeutic facilities.