Born on February 19, 1799, in Pittsburgh, Pennsylvania,[1] Wilkins graduated from Dickinson College in 1816 and read law in 1820.

[1] Following the admission of the State of Michigan to the Union on January 26, 1837, Wilkins was nominated by President Andrew Jackson on July 2, 1836, to the United States District Court for the District of Michigan, to a new seat authorized by 5 Stat.

[1] He was confirmed by the United States Senate on July 2, 1836, and received his commission on January 26, 1837.

[2] John M. Snowden, who stood high in favor with President Jackson, recommended Wilkins for appointment to the office of district court judge.

[citation needed] Shortly afterwards a friend of another applicant for the same office appeared before the President and denounced the man recommended by Mr. Snowden, as being utterly unfit for the place.