[5] Initial manifestations often include an abnormal segmental sweating response (described as hyperhidrosis or anhidrosis in some patients) and a tonic pupil.

Other commonly reported symptoms included fatigue, chronic cough, and increased urinary frequency.

[6] Ross syndrome is a non life-threatening benign condition but delay in diagnosis can result in slow progression of autonomic symptoms.

[7] Ross Syndrome is a progressive autonomic dysfunction that can occur in any age, ethnicity, or gender.

The average age of diagnosis for Ross syndrome is 36 years and affects more females than males.