Route 112 begins as South County Trail at US 1 in the center of Charlestown.

It heads north overlapped with Route 2 for several miles up to the intersection with Carolina Back Road.

The road name changes to Main Street as the route passes through the village center.

After leaving the village, Route 112 becomes Richmond Townhouse Road, continuing north for a few more miles until it ends at Route 138 near the Meadow Brook Golf Club.

[citation needed] The entire route is in Washington County.