It connects La Paz to Trinidad via Cororico, Caranavi, Yucumo, and San Ignacio de Moxos.

[1] Route 3 has a length of 610 km [1] kilometers and runs in an east-west direction.

It starts in the La Paz suburb of El Alto at a junction with Route 1.

[1] At the La Paz bus terminal, Route 3 turns off of Avenida Ismael Montes onto a one way street pair, and follows a windy road out of the city.

Leaving on the route of the Cororico River, the road runs over a mountain pass and a bridge over the Rio Beni.