The bishop on his appointment in 1550 found malpractice and theft of church property; and in a letter to the Lord Chancellor Thomas Goodrich accused Meyrick of 'shameless whoredom'; the details were recorded by John Foxe in his Acts and Monuments.
[1] Meyrick consequently refused to acknowledge the bishop's authority to make a visitation of the cathedral, and led the chapter in a factious opposition.
Of the bishop's three bitterest enemies, Thomas Young and George Constantine asked for his pardon before his martyrdom in 1555, but Meyrick did not.
On Elizabeth's accession, however, he was, with Richard Davies and Thomas Young, commissioned to visit the four Welsh dioceses, as well as Hereford and Worcester, and on 21 December 1559 he was consecrated by Parker to the see of Bangor in succession to William Glynn.
Francis, like his elder brother, served under and was knighted by the Earl of Essex in Ireland, died in 1603, and was buried in the Priory Church of Monkton, Pembroke, where his monument was destroyed during the civil wars; he was grandfather of Sir John Meyrick (d. 1659) .