It is managed by the University Hospitals of Derby and Burton NHS Foundation Trust.

[4] A new hospital was procured under a Private Finance Initiative contract to replace both the Derby City General Hospital and the Derbyshire Royal Infirmary in 2003.

The new hospital was built by Skanska at a cost of £333 million.

[5] It provides 200 single en-suite rooms and 4-bed bays for patients on its wards.

[7] The hospital is a major teaching centre for the University of Nottingham medical school including the graduate entry medical school (which is based at the Royal Derby Hospital site).