Rubratoxin

Rubratoxins are hepatotoxic mycotoxin produced by Penicillium rubrum and Penicillium purpurogenum.

Rubratoxin A and rubratoxin B have been known since 1950s.

[1] Rubratoxins are also known as protein phosphatase 2A (PP2A) specific inhibitor.

The PP2A inhibitory activity of rubratoxin A is about 100-fold higher than rubratoxin B [2] and rubratoxin A is now used as a chemical probe for PP2A research.

[3]