On 13 March 1842, the Boulevard du Jardin botanique had a population of 194 people.

[2] The high gate of the Botanical Garden opened into the Rue Royale.

[5] The Clinique Saint-Jean's medical facility was started in 1838 and completed in 1843, across from the Botanical Garden on the Boulevard du Jardin botanique.

[6][7] Originally located on the Boulevard du Jardin botanique, the Provincial Ophthalmic Institute of Brabant was founded and opened on 10 September 1849.

[8] At the intersection of the Rue Neuve/Nieuwstraat and the Boulevard du Jardin Botanique lies the Place Charles Rogier/Karel Rogierplein.