The Rue du Sergent Blandan (French pronunciation: [ʁy dy sɛʁʒɑ̃ blɑ̃dɑ̃] ⓘ) is one of the oldest streets of Lyon.

12 and 22 have respectively ancient inscriptions that say "en toy te fie" and "non domo dominus, sed domino domus", a quote from chapter 39 of Cicero's De officiis.

[1] The Confraternity of Penitents of the Holy Crucifix was installed in the street in 1633, and, during the Ancien Régime, was the owner of the chapel rebuilt in 1643[4] which was demolished during the Reign of Terror and replaced by a house that currently overlooks the montée de la Grande Côte.

On 8 February 2005, the city of Lyon installed a plaque as tribute to Jewish children of the school who were deported and killed during the Second World War.

[1] Among the famous inhabitants of the street, there are the painters Jacques Collet (1557) and Jean Montet (1785), and the designer Martin François (1887).