For men's basketball games, collapsible bleachers are expanded to cover two of the main gymnasium's three full courts and provide a seating capacity of 3,200.

[7] On July 22, 2020, Saint Peter’s University announced that through a $5 million lead gift from Thomas P. Mac Mahon, they would begin a phased renovation of the Yanitelli Center.

The renovation included the creation of a more modern basketball/volleyball arena with new retractable bleachers with an allotment of chairback seating, a full replacement of the hardwood court surface, updated branding and signage, a reimagined entryway to the facility, enhanced lighting and new video scoreboards.

[10] On March 3, 1977, the Yanitelli Center hosted the 1977 ECAC Tournament Semifinals of the Metropolitan region with the Seton Hall Pirates defeating the Army Black Knights 77–71.

[2] On January 9, 2008, the Yanitelli Center hosted a campaign rally for former president of the United States Barack Obama in his successful bid to become the Democratic candidate in the 2008 U.S. presidential election.

[13] On November 17, 2009, Saint Peter's hosted Monmouth University in a men's basketball game, with a 6:00 a.m. start time, as part of the second annual ESPN's 24–Hour College Hoops Tip-Off Marathon.

[2] In March of 2022, the arena hosted watch parties during Saint Peter's improbable Elite Eight run in the 2022 NCAA Division I men's basketball tournament.