[2] Rupandehi is named after Rupandevi temple which is situated in garden of Lumbini, where, the queen of King Suddhodana visited and give birth to Siddhartha Gautama Buddha.

Devdaha, the birthplace of Mayadevi (mother of Buddha), also lies in Rupandehi district.

At the time of the 2011 Nepal census, Rupandehi District had a population of 880,196 (432,193 male, 448,003 female) in 163,916 households.

[4] Ethnicity/caste: 15.9% were Hill Brahmin, 10.7% Magar, 9.7% Tharu, 8.3% Musalman, 7.4% Yadav, 6.8% Chhetri, 3.7% Chamar/Harijan/Ram, 3.1% Kami, 2.9% Lodh, 2.5% Kewat, 2.3% Kahar, 2.1% Newar, 2.0% Dhobi, 2.0% Gurung, 2.0% Kurmi, 2.0% Mallaha, 1.6% Kathabaniyan, 1.5% Dusadh/Pasawan/Pasi, 1.4% Teli, 1.1% Damai/Dholi, 0.9% Koiri/Kushwaha, 0.8% Baraee, 0.8% Hajam/Thakur, 0.7% other Terai, 0.7% Thakuri, 0.6% Terai Brahmin, 0.5% Kalwar, 0.5% Lohar, 0.5% Sanyasi/Dasnami, 0.5% Sarki, 0.4% Gaderi/Bhedidar, 0.4% Halwai, 0.4% Kumal, 0.2% Badhaee, 0.2% Bengali, 0.2% other Dalit, 0.2% Kayastha, 0.2% Marwadi, 0.2% Musahar, 0.2% Tamang, 0.1% Badi, 0.1% Chhantyal, 0.1% Dhandi, 0.1% Dhankar/Darikar, 0.1% Dhunia, 0.1% foreigners, 0.1% Gharti/Bhujel, 0.1% Majhi, 0.1% Mali, 0.1% Rai, 0.1% Rajbhar, 0.1% Rajput, 0.1% Thakali and 0.1% others.

The total area of the district is 1,360 km2 with 16.1% in Churia Range and rest in the Terai region.

In months of Shrawan (late July and early August), there is a big crowded fair, quite popular among locals and people around the regions.

This is a temple dedicated to Devi Satiya situated in Patkhauli VDC, near Rohini Khola In Rupandehi.

It is situated in Butwal City and is popular for the picnic spots, zoo and the gardens inside the park.

The greenery and the view of Rupandehi, Palpa and Kapilvastu districts is also another attraction in the park.

Thousands of Shiva's devotees from various parts of the country and from neighboring States of India visit to worship the Shivalinga inside the Bol Bam Dham.

Bol Bam is an annual pilgrimage glorifying Shiva made in Shraavana in which devotees travel barefooted wearing saffron robes in routes to the dham.

[19] Originally established by Chandra Sumsher, the present hospital came in operation in 2020 BS (1963-1964) with 50 beds.

[20] The hospital is led by orthopaedic surgeon Dr. Rajendra Sanjel Chhetri, Chairman of Nepal Orthopedic Association Lumbini, and is known for its high quality care and services.

Rupandehi is renowned at national level on education sector for its infrastructure and achievements.

The late Prime Minister Sushil Koirala laid a foundations stone of the airport on January 15.

[25] West Nepal Bus Entrepreneurs' Association established in 2026 with the approval of District Administration Office is the major provider of transportation services for Rupandehi and the whole country.

[27] Shakti Gauchan and Basanta Regmi are leading cricketers from Rupandehi who regularly play for the national team.

[30] Dipak Chhetri, Pukar Gahatraj, and Pradip Karki are notable footballer from Rupandehi.