[2][3] His strong season in 2002, when he batted .370 with 45 steals, led to the Toronto Blue Jays drafting him in the 1st round (14th overall) in the 2002 Major League Baseball Draft, ahead of Scott Kazmir, Nick Swisher, Cole Hamels, Jeff Francoeur, Matt Cain, and Canadian Joey Votto.

Adams finished the 2005 season with a .256 batting average, .325 OBP, 27 doubles, 5 triples, 8 home runs, and 11 stolen bases.

[11] On September 19, 2007, he recorded his first-ever major league grand slam, against Jonathan Papelbon of the Boston Red Sox.

While with Las Vegas, he played some games in the infield and outfield, and spent a month on the disabled list with a broken hand, but hit over .300 while active.

On June 21, Adams' contract was purchased from Triple-A by the Blue Jays, as Joe Inglett was optioned back to Las Vegas.

[13] On July 3, 2009, Adams was designated for assignment by the Blue Jays after they called up David Dellucci from Triple-A Las Vegas.

On April 15, 2010, he was injured turning a double play when Tug Hulett of the Pawtucket Red Sox, Boston's Triple-A affiliate, slid hard into him.

"[19][20] Adams returned from injury for the April 21, 2010, game against the Rochester Red Wings, singling in the top of the third inning, but not scoring.