Rutherford is a census-designated place (CDP) in Napa County, California, United States.

The Robert Mondavi Winery is located between Rutherford and neighboring Oakville (though its corporate headquarters are in nearby St. Helena).

Rutherford is located within the 11,887-acre (4,810 ha) Mexican land grant Rancho Caymus deeded to the early Napa Valley settler George C. Yount from General Mariano Guadalupe Vallejo in 1838 as payment for a variety of services.

Yount gave a 1,040-acre (421 ha) portion of the grant to his granddaughter Elizabeth and her husband Thomas Rutherford in 1864 as a wedding present.

[5] In August 2020, the Hennessey Fire was started by a lightning strike in the Vaca Mountains in the Rutherford area, resulting in widespread evacuations and the burning of over 315,611 acres (127,723 ha).

[6] According to the United States Census Bureau, the CDP covers an area of 1.7 square miles (4.4 km2), 99.76% of it land, and 0.24% water.