[1] In his final high school game in the state playoffs versus Evangel Christian Academy, Perrilloux accounted for 495 yards of offense.

[2] Some recruiting experts called him the most dangerous offensive weapon in the nation, noting his strong arm, quick release and pinpoint accuracy.

After remaining committed to Texas up to signing day, Perrilloux caved to local pressure and publicly announced he would attend Louisiana State to much pomp and circumstance.

[2] New LSU head coach Les Miles had only had the job for a few weeks, and Perrilloux was considered the cornerstone of a relatively small recruiting class.

[2] Perrilloux held a news conference on signing day and proclaimed he would win the Heisman Trophy as a true freshman.

"[4] Despite claims of competing for the Heisman Trophy as a true freshman, Perrilloux redshirted the 2005 season in order to learn the complex Jimbo Fisher offense.

[5] As the third-string quarterback for the 2006 Tigers behind juniors JaMarcus Russell and Matt Flynn, Perrilloux saw only limited playing time in 2006.

[6] It was reported by a Baton Rouge TV station on May 23, 2006, that Perrilloux desired to transfer to a junior college or Grambling State University.

[10] On May 22, 2007, LSU head coach Les Miles suspended Perrilloux from the football team indefinitely after the player was issued a misdemeanor summons by police when he allegedly tried to use his brother's driver's license to get onto the Hollywood Casino gambling boat.

Perrilloux was one of the candidates to replace JaMarcus Russell as LSU starting quarterback, but lost out to the more experienced Matt Flynn, a senior.

[12] On September 15, Perrilloux had his first start at quarterback for LSU, because Miles decided to rest regular starter Matt Flynn, who had sprained his right ankle a week earlier and whose participation in practice had been limited since.

On December 1, Perrilloux made his second start, this time in the SEC Championship Game versus Tennessee, replacing an injured Matt Flynn.

[16] The victory helped propel the Tigers to the BCS National Championship Game against Ohio State, after #1 Missouri and #2 West Virginia lost later that night.

[17] It was the second time since 2001 that a backup quarterback led LSU to the SEC Championship Game victory (Matt Mauck did it in 2001 versus Tennessee).

[23] He is reported to have a failed a drug test due to marijuana, missed a team meeting, skipped classes and was late for a handful of conditioning workouts.

After an opening loss to Georgia Tech, Perrilloux led JSU to an 8–3 season, completing 174 of 276 passes for 2,199 yards and 19 touchdowns.

[40] In 2016, Perrilloux played for the Aix-en-Provence Argonautes in the Ligue Élite de Football Américain in France with the team reaching the league semifinal game.