Sitton was raised in Irving, Texas with his three siblings by his mother and father, both high school science teachers.

[4] Sitton spent his early career working for oil and gas companies, including ALCOA, Oxy, Marathon, and Berwanger Engineering and Consulting.

[4] In 2012, Sitton lost a runoff contest with fellow Republican Greg Bonnen in Galveston County for the District 24 seat in the Texas House of Representatives.

[7] Incumbent officeholder Barry Smitherman decided to run, unsuccessfully, for state attorney general, thus creating an open seat.

[15] In 2019, Sitton was passed over for Railroad Commission chairman, a break from tradition since the incumbent closest to re-election is usually chosen.