While leading the Main of Round 14 at St. Louis, Villopoto came up short on a triple jump and leaped from his bike, landing hard.

[6] Later he won the inaugural Monster Energy Cup, claiming wins in the three heats to grab a US$1 million purse.

He finished 2011 leading Ryan Dungey by 12 points to claim the Lucas Oil Pro Motocross Championship.

It was Villopoto's third straight AMA Supercross Series championship, putting him in an elite class of off-road motorcycle champions – only Bob Hannah, Jeremy McGrath, and Ricky Carmichael have won three straight SX titles (Hannah ’77 – ’79, McGrath ”93 – ’96, ’98 – 2000, Carmichael ’01 – ’03).

On April 5, 2014, Villopoto won the 450cc Main Event at Houston's Reliant Stadium, bringing his total career Supercross All-Time Wins number to 38, making him 5th place overall behind Chad Reed.

On April 26, 2014, Villopoto dominated the highly competitive Supercross race at round 16 in New York, Metlife stadium, collecting his 6th win of the season (40th of career).

[11] At 18 years of age and his Des nations debut, Villopoto went 3-2 to win the MX2 class and secure his first victory at this event.