[3] The discovery of Non-cirrhotic portal fibrosis, an idiopathic chronic liver disease is attributed to him,[4] which he described in a 1962 medical paper, co-authored with Ramalingaswami and Wig.
[5] The Government of India awarded him the civilian honour of the Padma Shri in 2004 for his pioneering research on liver diseases including Non-cirrhotic portal fibrosis and Hepatitis B.
[8] Dr. Sama was born in 1934, did his graduate studies at the All India Institute of Medical Sciences Delhi and started his career by joining his alma mater, in 1958.
[3][9] His 1962 article is reported to be the first attempt at describing the chronic disease of Non-cirrhotic portal fibrosis and is also credited with recognised research on Hepatitis B.
[13][14] He is a former president and a life member of the Indian Society of Gastroenterology and has organised six therapeutic endoscopic workshops during his tenure there.