It is operated by DB Regio with class 423 electric multiple units.
The S19 runs until the early evening from Düren via Cologne to Blankenberg (Sieg), Herchen or Au (Sieg) on working days and between Düren and Hennef (Sieg) on Saturdays, Sundays and public holidays.
Services to/from Herchen or Au do not stop in Blankenberg.
It shares most of this route with line S12, but it runs through Cologne/Bonn Airport instead of through Porz.
[citation needed] The S13 is planned to operate between Bonn-Beuel and Düren every 20 minutes, while the S19 is planned to operate between Au (Sieg) and Köln-Nippes every 20 minutes.