[1] SAN was founded on January 21, 1964, providing commercial services within Ecuador with two Douglas C-47As.
Its arrival in Ecuador and entry into service marked a decided modernization of the flight equipment, which allowed the company to continue operating its usual routes and inaugurate direct flights from Cuenca to Quito and for the routes to Guayaquil to be operated with its own teams.
In 1975, three Sud Aviation Caravelle were acquired from TAP Air Portugal, two of them are put into service on the frequencies assigned between the cities of Quito and Guayaquil and one was stored in Cuenca for to serve as a source of spare parts.
In this period, the Cuenca investors who had a majority decided to sell their shares to a Guayaquil businessman.
In the early 1990s, SAN was absorbed by Ecuadorian airline SAETA, increasing its frequencies and fleet for national and international flights.