South Carolina Highway 391

It passes Neeses Pond and crosses Chinquapin Creek, where it enters Lexington County, before it curves to the northwest.

After it curves to the north, it crosses over Horsepen Creek and passes by Indian Trail Golf Course.

Just before entering the city limits of Batesburg-Leesville, the highway passes by Davis Pond and crosses over Duncan Creek.

The highway curves to the north-northeast and crosses over Gin Branch before intersecting the northern terminus of SC 245 (North Lee Street).

A short distance later, the highway starts heading to the north and crosses over the Little Saluda River.

It intersects the northern terminus of SC 194 (Denny Highway) just before crossing over the Saluda River on the Noah L. Black Bridge into Newberry County.