SC Preußen Stettin was a German association football club from the city of Stettin, Pomerania Province (today Szczecin, Poland).
In 1928, the team became Pomeranian champions and earned a second-place result in the subsequent regional Baltic championship, finishing behind VfB Königsberg.
That qualified SC for the national championship where they were put defeated 4–1 in the opening round by Holstein Kiel.
Following the 1933 re-organization of German football under the Third Reich into sixteen top-flight divisions, Stettin joined the western group of the Gauliga Pommern.
The combined side disappeared following World War II when Stettin became part of Poland.