In 1944 a group of orthodox Protestants left the Reformed Church, because they disagreed with Abraham Kuyper's view that God had created multiple branches of Christianity (Catholicism, Protestantism etc.

Former ARP MP Albertus Zijlstra chaired the congress, and also led the party in its early years.

Its sole MP, Laning, was asked to visit the queen to advise her on the formation of a new cabinet.

In 1963 the party finally entered the House of Representatives in the person of Pieter Jongeling, who was made top candidate on advice of prominent professor of theology J. Kamphuis.

This was rejected by the board of the GPV, who said that the party was open only to members of the liberated Reformed Church.

This started a slow process of cooperation between the GPV and the RPF, another orthodox Protestant party.

In 2003, the GPV officially disbanded, making its merger into the Christian Union final.

The GPV chose the name Gereformeerd Politiek Verbond (Reformed Political Alliance), because it wanted to convey that it was a reformed party, and that its organisation was decentralised: the GPV was primarily an alliance of local branches.

In 1967, the first manifesto of principles was published, in which the party again stressed that the Bible was the basis of their policy.

It scientific institute was the Groen van Prinsterer Stichting ("Groen van Prinsterer Foundation") and its education institute was Mandaat - Gereformeerd Politiek Vormingswerk ("Mandate, Reformed Political Education work").

The party had a small liberated Reformed pillar around, consisting out of like minded organisations.

Before 1981, the party was very isolated, this was caused by their own dogmatic position on non-liberated Christians.