Peptide transporter 1

656456643ENSG00000088386ENSMUSG00000025557P46059Q9JIP7NM_005073NM_053079NP_005064NP_444309Peptide transporter 1 (PepT 1) also known as solute carrier family 15 member 1 (SLC15A1) is a protein that in humans is encoded by SLC15A1 gene.

It functions in renal oligopeptide reabsorption and in the intestines in a proton dependent way, hence acting like a cotransporter.

[7] SLC15A1is localized to the brush border membrane of the intestinal epithelium and mediates the uptake of di- and tripeptides from the lumen into the enterocytes.

This protein also facilitates the absorption of numerous peptidomimetic drugs.

[8][9] This article incorporates text from the United States National Library of Medicine, which is in the public domain.

PepT 1 is a proton-coupled peptide cotransporter in epithelial cells.