658020517ENSG00000175003ENSMUSG00000023829O15245O08966NM_003057NM_153187NM_009202NP_003048NP_694857NP_033228Solute carrier family 22 member 1 is a protein that in humans is encoded by the gene SLC22A1.

[5][6] Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins.

The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein.

Two transcript variants encoding two different isoforms have been found for this gene, but only the longer variant encodes a functional transporter.

[7][8] This article incorporates text from the United States National Library of Medicine, which is in the public domain.