658220518ENSG00000112499ENSMUSG00000040966O15244O70577NM_153191NM_003058NM_013667NM_001355767NP_003049NP_038695NP_001342696Solute carrier family 22 member 2 (also termed OCT2 or organic cation transporter-2[5]) is a protein that in humans is encoded by the SLC22A2 gene.

[6][7] Poly specific organic cation transporters in the liver, kidney, intestine, and other organs are important for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins.

The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein.

It is found primarily in the kidney, where it may mediate the first step in cation reabsorption.

[7] This article incorporates text from the United States National Library of Medicine, which is in the public domain.