[5] SWEET1 is the sole transporter from the SLC50 (SWEET) gene family present in the genomes of most animal species, with the exception of the nematode Caenorhabditis elegans, which has seven.

[6] As the SWEET family has been identified relatively recently, the full range of its functions in animals is not yet clear.

[7] However, the bovine SLC50A1 homologue is associated with lactose concentration in milk,[8] and the CiRGA homologue in the sea squirt Ciona intestinalis is essential for tissue differentiation during embryogenesis, especially the development of the notochord.

[9] SWEET genes are common in plant genomes, with around twenty paralogues [6] functioning as both sucrose and hexose transporters, and are also associated with pathogen susceptibility.

This article on a gene on human chromosome 1 is a stub.