2823428253ENSG00000111700ENSMUSG00000030236Q9NPD5Q9JJL3NM_019844NM_001349920NM_020495NM_178235NP_062818NP_001336849NP_065241Solute carrier organic anion transporter family member 1B3 (SLCO1B3) also known as organic anion-transporting polypeptide 1B3 (OATP1B3) is a protein that in humans is encoded by the SLCO1B3 gene.

Normally expressed in the liver, the transporter functions to uptake large, non-polar drugs and hormones from the portal vein.

OATP1B3 has also been identified as a transporter aberrantly expressed in prostate cancer and implicated in prostate cancer progression.

[6] Increasing mRNA expression of OATP1B3 was also correlated to prostate cancer Gleason score.

[7] In addition, lower expression of OATP1B3 mRNA was also detected in testicular cancer.