Creators associated with SLG over the years include Evan Dorkin, Roman Dirge, Sarah Dyer, Woodrow Phoenix, Jhonen Vasquez, and Andi Watson.

The company's first wave of titles (Samurai Penguin, Barrabas, Lee Flea, and The Light) were all written by Vado, with art by a variety of creators.

[citation needed] Slave Labor Graphics's first major success was Samurai Penguin #1 by Vado and Mark Buck,[1] which sold 58,000 copies in the summer of 1986.

In this time period, comic book speculation was rampant, so Slave Labor Graphics was able to sell its entire print run of many titles.

In 2005, Slave Labor Graphics entered into a partnership with The Walt Disney Company to produce comic book series based on some of its properties: Haunted Mansion, Wonderland, Tron, and Gargoyles.