UC-63 was torpedoed and sunk by HMS E52 off Goodwin Sands on 1 November 1917; only one crewman survived the sinking.

UC-63 carried out nine war patrols, operating mainly in the North Sea against British fishing trawlers.

[5] The German government had made it clear they regarded the crews of merchant ships who fought back against U-boat attacks as francs-tireurs, and thus liable to execution.

[6] Before her loss in November 1917, UC-63 sank 36 ships, totalling 35,900 GRT, and damaged four more, in a nine month career.

[1] On 1 November 1917, while operating off the Goodwin Sands, UC-63 was sighted by British submarine HMS E52.