STARD7

5691099138ENSG00000084090ENSMUSG00000027367Q9NQZ5Q8R1R3NM_020151NM_139267NM_001385622NM_139308NM_001362684NP_064536NP_647469NP_001349613StAR-related lipid transfer domain protein 7 (STARD7) or gestational trophoblastic tumor gene-1 (GTT1) is a lipid transporter that specifically binds and transports phosphatidylcholine between membranes.

[5] When overproduced in the cell, mitochondrial levels of phosphatidylcholine rise.

StarD7-I possesses an additional 75 amino acids at its amino-terminus, which form a signaling sequence that targets it to the outer membrane of the mitochondrion.

[5] StarD7 contains a StAR-related transfer domain (START), from which it derives its name.

Moreover, the protein is a member of the predominantly phosphatidylcholine transporter subfamily of START proteins, the StarD2 subfamily.