The club is a product of a partnership in 2001 between Zultse VV and KSV Waregem, a former first division regular.

Zulte Waregem dropped to the 2013–14 UEFA Europa League play-off round, where they defeated APOEL, drawing 1–1 at home and winning 1–2 in Nicosia thanks to a late goal from Jens Naessens.

Finally, a loss against Rubin at home and Maribor's win over Wigan eliminated Zulte Waregem from the European competition.

[2] After a series of disappointing seasons in which the threat of relegation was narrowly avoided each time, things took a turn for the worse for head coach and club legend Francky Dury in the fall of 2021.

[3] The 2021–22 season was managed by assistants Timmy Simons and Davy De fauw, but they too failed to achieve results.

[4] In 2023, Zulte Waregem fell victim to the new league restructuring, which meant that there would be as many as three relegations that season.

Zulte, being the club with the statistically worst defence, ended up suffering relegation after 18 successive seasons in the top tier.

[5] Zulte Waregem plays its home matches at the Regenboogstadion, meaning "Rainbow Stadium" in Dutch.

Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.

Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.