She was the daughter of Goukouni Oueddei, who was head of state of Chad at the time, and was the youngest of twelve children.
In Tours, she became very involved in community life, including Catholic Relief Services, and she earned a master's degree in corporate law.
In 2011, Weddeye returned to N'Djamena, Chad, and worked as the legal adviser to the National Agency of Investment and Export.
On 26 January 2013 she was appointed to the government as Minister of Social Action, Family and National Solidarity in a cabinet reshuffle.
[2] It was believed that the First Lady of Chad, Hinda Deby, harbored some jealousy toward Weddeye.